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2011

  • Sun J, Cardani A, Sharma AK, Laubach VE, Jack RS, Müller W, Braciale TJ.
    Autocrine regulation of pulmonary inflammation by effector T-cell derived IL-10 during infection with respiratory syncytial virus.
    PLoS Pathog. 2011 Aug;7(8):e1002173.


  • Bröker B*, van Belkum A
    Immune proteomics of Staphylococcus aureus.
    PROTEOMICS. 2011; 11(15):3221-3231.


  • Burian M*, Grumann D, Holtfreter S, Wolz C, Goerke C, Bröker B
    Expression of staphylococcal superantigens during nasal colonization is not sufficient to induce a systemic neutralizing antibody response in humans.
    EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES. 2011; .


  • Chaudhry A*, Samstein RM, Treuting P, Liang Y, Pils MC, Heinrich J, Jack RS, Wunderlich FT, Brüning JC, Müller W, Rudensky AY
    Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation.
    IMMUNITY. 2011; 34(4):566-578.


  • Drude S*, Geissler A, Olfe J, Starke A, Domanska G, Schuett C, Kiank-Nussbaum C
    Side effects of control treatment can conceal experimental data when studying stress responses to injection and psychological stress in mice.
    LAB ANIMAL. 2011; 40(4):119-128.


  • Fotopoulou C*, Sehouli J, Pschowski R, VON Haehling S, Domanska G, Braicu E,  Fusch G, Reinke P, Schefold JC
    Systemic Changes of Tryptophan Catabolites via the Indoleamine-2,3-dioxygenase Pathway in Primary Cervical Cancer.
    ANTICANCER RESEARCH. 2011; 31(8):2629-2635.


  • Grumann D*, Ruotsalainen E, Kolata JB, Kuusela P, Järvinen A, Kontinen V, Bröker B, Holtfreter S
    Characterization of infecting strains and superantigen-neutralizing antibodies in Staphylococcus aureus bacteremia.
    Clinical and Vaccine Immunology. 2011; 18(3):487-493.


  • Holtfreter S*, Jursa-Kulesza J, Masiuk H, Verkaik NJ, de Vogel C, Kolata JB, Nowosiad M, Steil L, van Wamel W, van Belkum A, Völker U, Giedrys-Kalemba S, Bröker B
    Antibody responses in furunculosis patients vaccinated with autologous formalin-killed Staphylococcus aureus.
    EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES. 2011; 30(6):707-717.


  • Kolata JB*, Bode LGM, Holtfreter S, Steil L, Kusch H, Holtfreter B, Albrecht D, Hecker M, Engelmann S, van Belkum A, Völker U, Bröker B
    Distinctive patterns in the human antibody response to Staphylococcus aureus bacteremia in carriers and non-carriers.
    PROTEOMICS. 2011; 11(19): 3914-3927 .


  • Kusch K*, Hanke K, Holtfreter S, Schmudde M, Kohler C, Erck C, Wehland J, Hecker M, Ohlsen K, Bröker B, Engelmann S
    The influence of SaeRS and ?(B) on the expression of superantigens in different Staphylococcus aureus isolates.
    INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY. 2011; 301(6):488-499.


  • Wolf C*, Kusch H, Monecke S, Albrecht D, Holtfreter S, von Eiff C,  Petzl W, Rainard P, Bröker B, Engelmann S
    Genomic and proteomic characterization of Staphylococcus aureus mastitis isolates of bovine origin.
    PROTEOMICS. 2011; 11(12):2491-2502.

2010

  • Cziupka K*, Busemann A, Partecke LI, Pötschke C, Rath M, Traeger T, Menges P, von Bernstorff W, Kessler W, Diedrich S, Weiß FU, Maier S, Bröker B, Heidecke C
    Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) improves the innate immune response and enhances survival in murine polymicrobial sepsis
     CRITICAL CARE MEDICINE. 2010; 11(38):2169-2174.


  • Domanska G*, Motz C, Meinecke M, Harsman A, Papatheodorou P, Reljic B, Dian-Lothrop EA, Galmiche A, Kepp O, Becker L, Günnewig K, Wagner R, Rassow J
    Helicobacter pylori VacA toxin/subunit p34: targeting of an anion channel to the inner mitochondrial membrane.
    PLoS Pathogens. 2010; 4(6):78-82.


  • Kiank C*, Zeden J, Drude S, Domanska G, Fusch G, Otten W, Schuett C
    Psychological stress-induced, IDO1-dependent tryptophan catabolism: implications on immunosuppression in mice and humans.
    PLoS One. 2010; 5(7):e11825.


  • Krauel K*, Pötschke C, Weber C, Kessler W, Fürll B, Ittermann T, Maier S, Hammerschmidt S, Bröker B, Greinacher A
    Platelet factor 4 binds to bacteria-inducing antibodies cross-reacting with the major antigen in heparin-induced thrombocytopenia.
    BLOOD. 2010; 4(117):1370-1378.


  • Masiuk H*, Kopron K, Grumann D, Goerke CR, Kolata JB, Giedrys-Kalemba S, Bröker B, Holtfreter S
    Recurrent furunculosis - associations with Panton-Valentine leukocidin and the genetic background of Staphylococcus aureus.
     JOURNAL OF CLINICAL MICROBIOLOGY. 2010; 5(48):1527-1535.


  • Sonnemann J*, Friebe E, Schmudde M, Beck M, Bröker B
    Histone deacetylase inhibitors prevent activation of tumour-reactive NK cells and T cells but do not interfere with their cytolytic effector functions.
    CANCER LETTERS. 2010; .


  • Peters B*, Kuttler B, Beineke A, Lorenz G, Thiele A, Nicolai O, Rettig R, Mullins JJ, Peters J The renin-angiotensin system as a primary cause of polyarteritis nodosa in rats.
    JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2010; 14(6A):1318-1327.


  • Pils MC, Pisano F, Fasnacht N, Heinrich JM, Groebe L, Schippers A, Rozell B, Jack RS, Müller W
    Monocytes/macrophages and/or neutrophils are the target of IL-10 in the LPS endotoxemia model.
    Eur J Immunol. 2010 Feb;40(2):443-8.


  • Vogelgesang A*, Grunwald U, Bakkebo M, May VEL, Langner S, Wallaschofski H, Kessler C, Bröker B, Dressel A
    Functional status of peripheral blood T-cells in ischemic stroke patients
    PLoS One. 2010; 1(5):e8718-20.


  • Zautner AE*, Krause M, Stropahl G, Holtfreter S, Frickmann H, Maletzki C, Kreikemeyer B, Pau HW, Podbielski A
    Intracellular persisting Staphylococcus aureus is the major pathogen in recurrent tonsillitis.
    PLoS One. 2010; 5(3):e9452.


  • Dummer A*, Sendler M, Weiß FU, Pötschke C, Sparwasser T, Halangk W, Bröker B, Lerch M, Mayerle J
    Regulatory T-cells mediate the compensatory anti-inflammatory Response Syndrome (CARS) in severe acute Pancreatitis
    PANCREATOLOGY. 2010; (10):305.


  • Ziebandt A*, Kusch H, Degner M, Jaglitz S, Sibbald MJJB, Arends JP, Chlebowicz MA, Albrecht D, Pantucek R, Doskar J, Ziebuhr W, Bröker B, Hecker M, van Dijl JM, Engelmann S
    Proteogenomics uncovers exteme heterogeneity of the Staphylococcus aureus exoproteome due to genomic plasticity and variant gene regulation
    PROTEOMICS. 2010; (10):1634-1644.


  • Schmudde M*, Sonnemann J, Bröker B, Beck J
    The histone deacetylase inhibitors prevent activation of tumour-reactive NK cells and T cells but do not interfere with their cytolytic effector functions.
    CANCER LETTERS. 2010; :173-181.


2009

  • Holtfreter S, Nguyen T T H, Wertheim H, Steil L, Kusch H, Truong Q P, Engelmann S, Hecker M, Völker U, van Belkum , Bröker B.
    Anti-Staphylococcus aureus antibody profiles in carriers and noncarriers
    .
    Clin Vaccine Immunol 2009


  • Nicolai O, Rettig R, Mullins J J.
    The renin-angiotensin system as a primary cause of polyarteritis nodosa in rats
    .
    J Cell Mol Med 2009 


  • Zeden J-P, Fusch G, Holtfreter B, Schefold J, Reinke P, Domanska G, Haas J-P, Gründling M, Westerholt A, Schütt Ch. Excessive tryptophan catabolism along the kynurenine pathway precedes ongoing sepsis in critically ill patients.
    Anaesth Intens Care 2009 

  • Verkaik NJ, de Vogel CP, Boelens HA, Grumann D, Hoogenboezem T, Vink C, Hooijkaas H, Foster TJ, Verbrugh HA, van Belkum A, van Wamel WJ.
    Anti-Staphylococcal Humoral Immune Response in Persistent Nasal Carriers and Noncarriers of Staphylococcus aureus.

    J Infect Dis 2009, 199(5):625-632
    PMID: 19199541 [PubMed - indexed for MEDLINE]

  • Fischer A, Francois P, Holtfreter S, Bröker B, Schrenzel J.
    Development and evaluation of a rapid strategy to determine enterotoxin gene content in Staphylococcus aureus.

    J Microbiol Meth 2009, 77(2):184-90

  • Goerke C R, Pantucek R, Holtfreter S, Schulte B, Zink M, Grumann D, Bröker B, Dosgar J, Wolz C. Diversity of prophages in dominant Staphylococcus aureus clonal lineages.
    J Bacteriol 2009, 119:3462-3468

  • Depke M, Steil L, Domanska G, Völker U, Schütt Ch, Kiank C.
    Altered hepatic mRNA expression of immune response and apoptosis-associated genes after acute and chronic psychological stress in mice.
    Mol Immunol 2009, 46(15):3018-28


  • Schefold J, Zeden J-P, Fotopoulou CH, von Haehling S, Pschowski R, Hasper D, Volk H-D, Schütt Ch, Reinke P.
    Increased indoleamine 2,3-dioxygenase (IDO) activity and elevated serum levels of tryptophan catabolites in patients with chronic kidney disease: a possible link between chronic inflammation and uremic symptoms.
    Nephrol Dial Transpl 2009, 24(6):1901-8 
    PMID: 18573 [PubMed - as supplied by publisher]

2008

  • Depke M, Fusch G, Domanska G, Geffers R, Völker U, Schütt Ch, Kiank C.
    Hypermetabolic syndrome as a consequence of repeated psychological stress in mice .
    Endocrinology 2008, 149(6):2714-2723
    PMID: 11701[PubMed - in process]
     
  • Schmudde M, Braun A, Pende D, Sonnemann J, Klier U, Beck J, Moretta L, Bröker B.
    Histone deacetylase inhibitors sensitize tumour cells for cytotoxic effects of natural killer cells. Cancer Lett 2008 272:110-121

  • Kiank C, Daeschlein G, Schütt C.
    Pneumonia as a long-term consequence of chronic psychological stress in BALB/c mice.
    Brain Behav Immun 2008 online
    PMID: 18571893 [PubMed - as supplied by publisher]

  • Mauermann N,von Garnier CH, Tamm M, Bingisser R,Burian J, Schütt C, Germano D, Eriksson U.
    Interferon gamma regulates idiopathic pneumonia syndrome, a Th17+CD4+ T-cell-mediated GvH Disease.
    Am J Resp Crit Care 2008 178(4):379-88
    PMID: 18511701[PubMed - in process]

  • Depke M, Fusch G, Domanska G, Geffers R, Völker U, Schütt C, Kiank C.
    Hypermetabolic syndrome as a consequence of repeated psychological stress in mice.
    Endocrinology 2008, 149(6):2714-23
    PMID: 18325986 [PubMed - indexed for MEDLINE]

  • Klabunde M, Traeger T, Pötschke CH, Billing A, Dummer A, Friebe E, Kiank C, Grunwald U, Jack R S, Schütt C, Heidecke C-D, Maier S, Bröker B.
    Detrimental role for CD4+ T lymphocytes in murine diffuse peritonitis due to inhibition of local bacterial elimination.
    Gut. 2008, 57:188-195
    PMID: 17965062 [PubMed - indexed for MEDLINE]

  • Vogelgesang A, Grunwald U, Langner S, Jack R S, Bröker B, Kessler CH, Dressel A.
    Analysis of Lymphocyte Subsets in Patients With Stroke and Their Influence on Infection After Stroke.
    Stroke. 2008, 39(1):237-241
    PMID: 18048864 [PubMed - indexed for MEDLINE]

2007

  • Kiank C, Entleutner M, Fürll B, Westerholt A, Heidecke C-D, Schütt C
    Stress-induced immune conditioning affects the course of experimental peritonitis.
    Shock. 2007, 27(3):305-311
    PMID: 17304112 [PubMed - indexed for MEDLINE]

  • Kiank C, Körner P, Keßler W, Traeger T, Maier S, Heidecke C-D, Schütt C
    Seasonal variations in inflammatory responses to sepsis ad stress in mice.
    Crit Care Med. 2007, 35(10):2352-2358
    PMID: 17944025 [PubMed - indexed for MEDLINE]

  • Howard JC, Jack RS.
    Evolution of immunity and pathogens.
    Eur J Immunol. 2007, 37(7):1721-3. Review.
    PMID: 1758719 [PubMed - indexed for MEDLINE]

  • Scholz F, López de Lara González G, Machado de Carvalho L, Hilgemann M, Brainina KZ, Kahlert H, Jack RS, Minh DT.
    Indirect electrochemical sensing of radicals and radical scavengers in biological matrices.
    Angew Chem Int Ed Engl. 2007, 46(42):8079-81.
    PMID: 17868166 [PubMed - indexed for MEDLINE]

  • Rogasch K, Rühmling V, Pane-Farre J, Höper D, Weinberg CH, Fuchs S, Schmudde M, Bröker B, Wolz C, Hecker M, Engelmann S.
    Influence of the two-component system SaeRS on global gene expression in two different Staphylococcus aureus strains.
    J Bacteriol. 2006, 188(22):7742-58
    PMID: 17079681 [PubMed - indexed for MEDLINE]

  • Grabarczyk P, Przybylski G, Depke M, Völker U, Bahr J, Assmus K, Bröker B, Walther R, Schmidt CH.
    Inhibition of BCL11B expression leads to apoptosis of malignant but not normal mature T cells.
    Oncogene. 2007, 26:3797-810
    PMID: 17173069 [PubMed - indexed for MEDLINE]

  • Sonnemann J, Dreyer L, Hartwig M, Palani C D, Hong L T T, Klier U, Bröker B, Völker U, Beck J.
    Histone deacetylase inhibitors induce cell death and enhance the apoptosis-inducing activity of TRAIL in Ewing's sarcoma cells.
    J Cancer Res Clin. 2007, 133(11):847-858
    PMID: 17486365 [PubMed - indexed for MEDLINE]

  • Holtfreter S, Grumann D, Schmudde M, Nguyen T T H, Eichler P, Stommenger B, Kopron K, Kolata J, Giedrys-Kalemba S, Steinmetz I, Witte W, Bröker B.
    Clonal distribution of superantigen genes in clinical Staphylococcus aureus isolates.
    J Clin Microbiol. 2007, 45(8):2669-2680
    PMID: 17537946 [PubMed - indexed for MEDLINE]

2006

  • Kiank C, Holtfreter B, Starke A, Mundt A, Wilke C, Schütt C
    Stress susceptibility predicts the severity of immune depression and the failure to combat bacterial infections in chronically stressed mice.
    Brain Behav Immun. 2006, 20(4):359-368
    PMID: 16330179 [PubMed - indexed for MEDLINE]

  • Holtfreter B, Bandt C, Kuhn S-O, Grunwald U, Lehmann C, Schütt C, Gründling M
    Serum Osmolality and Outcome in ICU Patients.
    Acta Anaesthesiol Scand. 2006 Sep;50(8):970-7
    PMID: 16923092 [PubMed - indexed for MEDLINE]

  • Kumar S, Jack RS
    Origin and differentiation of macrophages and of myeloid Dendritic cells.
    J Endotoxin Res. 2006
  • 12(5):278-284
    PMID: 17059691 [PubMed - indexed for MEDLINE]

  • Holtfreter S, Roschack K, Eichler P, Eske K, Holtfreter B, Kohler C, Engelmann S, Hecker M, Greinacher A, Broker BM
    Staphylococcus aureus carriers neutralize superantigens by antibodies specific for their colonizing strain: a potential explanation for their improved prognosis in severe sepsis.
    J Infect Dis. 2006 May 1;193(9):1275-8.
    PMID: 16586365 [PubMed - indexed for MEDLINE]

2005

  • Holtfreter S, Broker BM
    Staphylococcal superantigens: do they play a role in sepsis?
    Arch Immunol Ther Exp (Warsz). 2005 Jan-Feb;53(1):13-27. Review.
    PMID: 15761373 [PubMed - indexed for MEDLINE]
     


2004

  • Holtfreter S, Bauer K, Thomas D, Feig C, Lorenz V, Roschack K, Friebe E, Selleng K, Lövenich S, Greve T, Greinacher A, Panzig B, Engelmann S, Lina G, Bröker BM
    egc-Encoded superantigens from Staphylococcus aureus are neutralized by human sera much less efficiently than are classical staphylococcal enterotoxins or toxic shock syndrome toxin.
    Infect Immun. 2004 Jul;72(7):4061-71.
    PMID: 15213151 [PubMed - indexed for MEDLINE]

  • Klöting N, Klöting I, Jack RS
    CD14 triggers autoimmune Type 1 diabetes in the NOD mouse.
    Diabetologia. 2004 Jan;47(1):151-2. Epub 2003 Nov 12. No abstract available.
    PMID: 14614560 [PubMed - indexed for MEDLINE]

  • Graefe SEB, Jacobs T, Wächter U, Bröker BM, Fleischer B
    CTLA-4 regulates the murine immune response to Trypanosoma cruzi infection.
    Parasite Immunol. 2004 Jan;26(1):19-28.
    PMID: 15198642 [PubMed - indexed for MEDLINE]

  • Sachse K, Grossmann E, Berndt A, Schütt C, Henning K, Theegarten D, Anhenn O, Reinhold P
    Respiratory chlamydial infection based on experimental aerosol challenge of pigs with Chlamydia suis.
    Comp Immunol Microbiol Infect Dis. 2004 Jan;27(1):7-23.
    PMID: 14656538 [PubMed - indexed for MEDLINE]

  • Frank J, Witte K, Schrödl W, Schütt C
    Chronic alcoholism causes deleterious conditioning of innate immunity.
    Alcohol Alcohol.  2004 Sep-Oct; 39(5):386-92. Epub 2004 Aug 02..
    PMID: 15289211 [PubMed - in process]

  • Schütt C
    Grundlagen der Immunologie für den praktisch tätigen Arzt.
    Internistische Praxis 44, 519-530 ( 2004)
    tägl. prax. 45, 39-60 (2004)
    link

2003
  • Schröder D, Wachlin G, Klöting I, Schmidt S.
    Cytokine sensitivity of Langerhans' islets of diabetes-prone BB/OK rats under hypoglycemic conditions.
    Autoimmunity. 2003 Jun;36(4):211-9.
    PMID: 14563014 [PubMed - indexed for MEDLINE]

  • Wachlin G, Augstein P, Schröder D, Kuttler B, Klöting I, Heinke P, Schmidt S.
    IL-1beta, IFN-gamma and TNF-alpha increase vulnerability of pancreatic beta cells to autoimmune destruction.
    J Autoimmun. 2003 Jun;20(4):303-12.
    PMID: 12791316 [PubMed - indexed for MEDLINE]

  • Braun N, Gärtner C, Marfo Y, Browne NEL, Zipfel P, Müller-Myhsok B, Fleischer B, Bröker BM
    CTLA-4 positive T cells in contrast to procalcitonin plasma levels discriminate between severe and uncomplicated Plasmodium falciparum malaria in Ghanaian children.
    Trop Med Int Health. 2003 Nov;8(11):1018-24.
    PMID: 14629769 [PubMed - indexed for MEDLINE]


2002
  • Breloer M, More SH, Osterloh A, Stelter F, Jack RS, Bonin Av A.
    Macrophages as main inducers of IFN-gamma in T cells following administration of human and mouse heat shock protein 60.
    Int Immunol. 2002 Nov;14(11):1247-53.
    PMID: 12407015 [PubMed - indexed for MEDLINE]

  • Yang KK, Dorner BG, Merkel U, Ryffel B, Schütt C, Golenbock D, Freeman MW, Jack RS
    Neutrophil influx in response to a peritoneal infection with Salmonella is delayed in lipopolysaccharide-binding protein or CD14-deficient mice.
    J Immunol. 2002 Oct 15;169(8):4475-80.
    PMID: 12370383 [PubMed - indexed for MEDLINE]

  • Jack RS, Schütt C, Bröker BM
    The guardians at the gate.
    Trends Immunol. 2002 Sep;23(9):423-4.
    PMID: 12200055 [PubMed - indexed for MEDLINE]

  • Berner R, Fürll B, Stelter F, Drose J, Müller HP, Schütt C
    Elevated levels of lipopolysaccharide-binding protein and soluble CD14 in plasma in neonatal early-onset sepsis.
    Clin Diagn Lab Immunol. 2002 Mar;9(2):440-5.
    PMID: 11874891 [PubMed - indexed for MEDLINE]

  • Herrmann C, Spreitzer I, Schröder NW, Morath S, Lehner MD, Fischer W, Schütt C, Schumann RR, Hartung TT
    Cytokine induction by purified lipoteichoic acids from various bacterial species--role of LBP, sCD14, CD14 and failure to induce IL-12 and subsequent IFN-gamma release.
    Eur J Immunol. 2002 Feb;32(2):541-51.
    PMID: 11828371 [PubMed - indexed for MEDLINE]

  • Schäfer C, Parlesak A, Schütt C, Bode JC, Bode C
    Concentrations of lipopolysaccharide-binding protein, bactericidal/permeability-increasing protein, soluble CD14 and plasma lipids in relation to endotoxaemia in patients with alcoholic liver disease.
    Alcohol Alcohol. 2002 Jan-Feb;37(1):81-6.
    PMID: 11825862 [PubMed - indexed for MEDLINE]

  • Schröder D, Ratke M, Bauer UC, Klöting I, Ziegler B, Schmidt S
    Prophylactic Insulin Treatment of Diabetis-prone BB/OK Rats by Application of a Sustained Release Insulin Implant.
    Autoimmunity. 2002 Vol.35 (2):143-153.
    PMID: 12071437 [PubMed - in process]



2001
  • Echtenacher B, Freudenberg MA, Jack RS, Männel DN
    Differences in innate defense mechanisms in endotoxemia and polymicrobial septic peritonitis.
    Infect Immun. 2001 Dec;69(12):7271-6.
    PMID: 11705897 [PubMed - indexed for MEDLINE]

  • Pfeiffer A, Böttcher A, Orso E, Kapinsky M, Nagy P, Bodnar A, Spreitzer I, Liebisch G, Drobnik W, Gempel K, Horn M, Holmer S, Hartung T, Multhoff G, Schutz G, Schindler H, Ulmer AJ, Heine H, Stelter F, Schütt C, Rothe G, Szollosi J, Damjanovich S, Schmitz G
    Lipopolysaccharide and ceramide docking to CD14 provokes ligand-specific receptor clustering in rafts.
    Eur J Immunol. 2001 Nov;31(11):3153-64.
    PMID: 11745332 [PubMed - indexed for MEDLINE]

  • Steiner K, Moosig F, Csernok E, Selleng K, Gross WL, Fleischer B,Bröker BM
    Increased expression of CTLA-4 (CD152) by T and B lymphocytes in Wegener's granulomatosis.
    Clin Exp Immunol. 2001 Oct;126(1):143-50.
    PMID: 11678911 [PubMed - indexed for MEDLINE]

  • Greve T, Tamgüney T, Fleischer B, Fickenscher H, Bröker BM
    Downregulation of p56(lck) tyrosine kinase activity in T cells of squirrel monkeys (Saimiri sciureus) correlates with the nontransforming and apathogenic properties of herpesvirus saimiri in its natural host.
    J Virol. 2001 Oct;75(19):9252-61.
    PMID: 11533187 [PubMed - indexed for MEDLINE]

  • Heinrich JM; Bernheiden M, Minigo G, Yang KK, Schütt C, Mannel DN, Jack RS
    The essential role of lipopolysaccharide-binding protein in protection of mice against a peritoneal Salmonella infection involves the rapid induction of an inflammatory response.
    J Immunol. 2001 Aug 1;167(3):1624-8.
    PMID: 11466385 [PubMed - indexed for MEDLINE]

  • Barlage S, Fröhlich D, Böttcher A, Jauhiainen M, Müller HP; Noetzel F, Rothe G, Schütt C, Linke RP, Lackner KJ, Ehnholm C, Schmitz G
    ApoE-containing high density lipoproteins and phospholipid transfer protein activity increase in patients with a systemic inflammatory response.
    J Lipid Res. 2001 Feb;42(2):281-90.
    PMID: 11181759 [PubMed - indexed for MEDLINE]

  • Bernheiden M, Heinrich JM, Minigo G, Schütt C, Stelter F, Freeman M, Golenbock D, Jack RS
    LBP, CD14, TLR4 and the murine innate immune response to a peritoneal Salmonella infection.
    J Endotoxin Res. 2001;7(6):447-50.
    PMID: 11753215 [PubMed - indexed for MEDLINE]


2000
  • Schlotmann T, Waase I, Jülch C,Klauenberg U, Müller-Mysok B,Dietrich M, FleischerB, Bröker BM
    CD4 alphabeta T lymphocytes express high levels of the T lymphocyte antigen CTLA-4 (CD152) in acute malaria.
    J Infect Dis. 2000 Jul;182(1):367-70. Epub 2000 Jun 30.
    PMID: 10882627 [PubMed - indexed for MEDLINE]

  • Jack RS
    Introduction: hunting devils.
    Chem Immunol. 2000;74:1-4. Review. No abstract available.
    PMID: 10608078 [PubMed - indexed for MEDLINE


1999
  • Stelter F, Loppnow H, Menzel R, Grunwald U, Bernheiden M, Jack RS, Ulmer AJ, Schütt C
    Differential impact of substitution of amino acids 9-13 and 91-101 of human CD14 on soluble CD14-dependent activation of cells by lipopolysaccharide.
    J Immunol. 1999 Dec 1;163(11):6035-44.
    PMID: 10570291 [PubMed - indexed for MEDLINE]

  • Fan X, Stelter F, Menzel R, Jack RS, Spreitzer I, Hartung T, Schütt C
    Structures in Bacillus subtilis are recognized by CD14 in a lipopolysaccharide binding protein-dependent reaction.
    Infect Immun. 1999 Jun;67(6):2964-8.
    PMID: 10338506 [PubMed - indexed for MEDLINE]

  • Schütt C
    CD14.
    Int J Biochem Cell Biol. 1999 May;31(5):545-9. Review.
    PMID: 10399315 [PubMed - indexed for MEDLINE]

  • Wiegand G, Selleng K, Gründling M, Jack RS
    Isolation of highly enriched human monocytes from ten ml samples of heparinised whole blood.
    Clin Chem Lab Med. 1999 Mar;37(3):369-72.
    PMID: 10353485 [PubMed - indexed for MEDLINE]

  • Wiegand G, Selleng K, Gründling M, Jack RS
    Gene expression pattern in human monocytes as a surrogate marker for systemic inflammatory response syndrome (SIRS).
    Mol Med. 1999 Mar;5(3):192-202.
    PMID: 10404516 [PubMed - indexed for MEDLINE]

  • Jack RS, Wiegand G
    Analysis of the "innate" immune system
    Mycoses. 1999;42 Suppl 1:35-8. Review. German. No abstract available.
    PMID: 10592713 [PubMed - indexed for MEDLINE]

  • Schütt C
    Fighting infection: the role of lipopolysaccharide binding proteins CD14 and LBP.
    Pathobiology. 1999;67(5-6):227-9. Review.
    PMID: 10725789 [PubMed - indexed for MEDLINE]

  • Schütt C
    Maternal anti-paternal reactivity--depends on etiology
    Zentralbl Gynakol. 1999;121(4):202-5. Review. German.
    PMID: 10355099 [PubMed - indexed for MEDLINE]


1998
  • Neumeister B, Faigle M, Sommer M, Zahringer U, Stelter F, Menzel R, Schütt C, Northoff H
    Low endotoxic potential of Legionella pneumophila lipopolysaccharide due to failure of interaction with the monocyte lipopolysaccharide receptor CD14.
    Infect Immun. 1998 Sep;66(9):4151-7.
    PMID: 9712761 [PubMed - indexed for MEDLINE]

  • Stelter F, Witt S, Fürll B, Jack RS, Hartung T, Schütt C
    Different efficacy of soluble CD14 treatment in high- and low-dose LPS models.
    Eur J Clin Invest. 1998 Mar;28(3):205-13.
    PMID: 9568466 [PubMed - indexed for MEDLINE]

  • Aasted B, Gori K, Dominguez J, Ezquerra A, Bullido R, Arn S, Bianchi A, Binns R, Chu RM, Davis WC, Denham S, Haverson K, Jensen KT, Kim YB, Magyar A, Petersen KR, Saalmüller A, Sachs D, Schütt C, Shimizu M, Stokes C, Whittall T, Yang H, Zuckermann F
    Immunoprecipitation studies of monoclonal antibodies submitted to the Second International Swine CD Workshop.
    Vet Immunol Immunopathol. 1998 Jan 30;60(3-4):229-36.
    PMID: 9589561 [PubMed - indexed for MEDLINE]

  • Stelter F, Bernheiden M, Menzel R, Witt S, Jack RS, Grunwald U, Fan X, Schütt C
    The molecular basis for therapeutic concepts utilizing CD14.
    Prog Clin Biol Res. 1998;397:301-13.
    PMID: 9575571 [PubMed - indexed for MEDLINE]


1997
  • Jack RS, Fan X, Bernheiden M, Rune G, Ehlers M, Weber A, Kirsch G, Mentel R, Fürll B, Freudenberg M, Schmitz G, Stelter F, Schütt C
    Lipopolysaccharide-binding protein is required to combat a murine Gram-negative bacterial infection.
    Nature. 1997 Oct 16;389(6652):742-5.
    PMID: 9338787 [PubMed - indexed for MEDLINE]

  • Schütt C, Fürll B, Stelter F, Jack RS, Witt S
    CHO transfectants produce large amounts of recombinant protein in suspension culture.
    J Immunol Methods. 1997 May 12;204(1):99-102.
    PMID: 9202714 [PubMed - indexed for MEDLINE]

  • Stelter F, Bernheiden M, Menzel R, Jack RS, Witt S, Fan X, Pfister M, Schütt S
    Mutation of amino acids 39-44 of human CD14 abrogates binding of lipopolysaccharide and Escherichia coli.
    Eur J Biochem. 1997 Jan 15;243(1-2):100-9.
    PMID: 9030727 [PubMed - indexed for MEDLINE]


1996
  • Grunwald U, Fan X, Jack RS, Workalemahu G, Kallies A, Stelter F, Schütt C
    Monocytes can phagocytose Gram-negative bacteria by a CD14-dependent mechanism.
    J Immunol. 1996 Nov 1;157(9):4119-25.
    PMID: 8892647 [PubMed - indexed for MEDLINE]

  • Stelter F, Pfister M, Bernheiden M, Jack RS, Bufler P, Engelmann H, Schütt C
    The myeloid differentiation antigen CD14 is N- and O-glycosylated. Contribution of N-linked glycosylation to different soluble CD14 isoforms.
    Eur J Biochem. 1996 Mar 1;236(2):457-64.
    PMID: 8612616 [PubMed - indexed for MEDLINE]


1995
  • Mitzner S, Stange J, Pichel K, Handschuk I, Korten G, Ehlers M, Schütt C, Schmidt R
    Increased soluble CD14 levels in patients on hemodialysis. Influence of dialysate endotoxin or incompatibility to dialyzer membranes?
    ASAIO J. 1995 Jul-Sep;41(3):M707-8.
    PMID: 8573897 [PubMed - indexed for MEDLINE]

  • Schütt C, Schilling T, Grunwald U, Stelter F, Witt S, Krüger C, Jack RS
    Human monocytes lacking the membrane-bound form of the bacterial lipopolysaccharide (LPS) receptor CD14 can mount an LPS-induced oxidative burst response mediated by a soluble form of CD14.
    Res Immunol. 1995 Jul-Aug;146(6):339-50.
    PMID: 8719658 [PubMed - indexed for MEDLINE]

  • Jack RS, Grunwald U, Stelter F, Workalemahu G, Schütt C
    Both membrane-bound and soluble forms of CD14 bind to Gram-negative bacteria.
    Eur J Immunol. 1995 May;25(5):1436-41.
    PMID: 7539760 [PubMed - indexed for MEDLINE]

  • Loppnow H, Stelter F, Schonbeck U, Schluter C, Ernst M, Schütt C, Flad HD
    Endotoxin activates human vascular smooth muscle cells despite lack of expression of CD14 mRNA or endogenous membrane CD14.
    Infect Immun. 1995 Mar;63(3):1020-6.
    PMID: 7532623 [PubMed - indexed for MEDLINE]

  • Bufler P, Stiegler G, Schuchmann M, Hess S, Krüger C, Stelter F, Eckerskorn C, Schütt C, Engelmann H
    Soluble lipopolysaccharide receptor (CD14) is released via two different mechanisms from human monocytes and CD14 transfectants.
    Eur J Immunol. 1995 Feb;25(2):604-10.
    PMID: 7533093 [PubMed - indexed for MEDLINE]

  • Schütt C, Schilling T, Stelter F, Fürll B, Krüger C, Witt S, Jack R, Grunwald U
    Modalities of endotoxin binding to CD14.
    Prog Clin Biol Res. 1995;392:339-48.
    PMID: 8524939 [PubMed - indexed for MEDLINE]


1994
  • Schletter J, Krüger C, Lottspeich F, Schütt C
    Improved method for preparation of lipopolysaccharide-binding protein from human serum by electrophoretic and chromatographic separation techniques.
    J Chromatogr B Biomed Appl. 1994 Mar 18;654(1):25-34.
    PMID: 7516248 [PubMed - indexed for MEDLINE]

  • Pforte A, Schiessler A, Gais P, Beer B, Ehlers M, Schütt C, Ziegler-Heitbrock HW
    Expression of CD14 correlates with lung function impairment in pulmonary sarcoidosis.
    Chest. 1994 Feb;105(2):349-54.
    PMID: 7508361 [PubMed - indexed for MEDLINE]

  • Ziegler-Heitbrock HW, Schraut W, Wendelgass P, Strobel M, Sternsdorf T, Weber C, Aepfelbacher M, Ehlers M, Schütt C, Haas JG
    Distinct patterns of differentiation induced in the monocytic cell line Mono Mac 6.
    J Leukoc Biol. 1994 Jan;55(1):73-80.
    PMID: 8283142 [PubMed - indexed for MEDLINE]


1993
  • Pforte A, Schiessler A, Gais P, Beer B, Strobel M, Ehlers M, Schütt C, Ziegler-Heitbrock HW
    Increased expression of the monocyte differentiation antigen CD14 in extrinsic allergic alveolitis.
    Monaldi Arch Chest Dis. 1993 Dec;48(6):607-12.
    PMID: 7510201 [PubMed - indexed for MEDLINE]

  • Ziegler-Heitbrock HW, Fingerle G, Strobel M, Schraut W, Stelter F, Schütt C, Passlick B, Pforte A
    The novel subset of CD14+/CD16+ blood monocytes exhibits features of tissue macrophages.
    Eur J Immunol. 1993 Sep;23(9):2053-8.
    PMID: 7690321 [PubMed - indexed for MEDLINE]

  • Schütt C, Schumann R
    The endotoxin receptor CD14
    Immun Infekt. 1993 Apr;21(2):36-40. Review. German.
    PMID: 7687987 [PubMed - indexed for MEDLINE]

  • Grunwald U, Krüger C, Schütt C
    Endotoxin-neutralizing capacity of soluble CD14 is a highly conserved specific function.
    Circ Shock. 1993 Mar;39(3):220-5.
    PMID: 7680967 [PubMed - indexed for MEDLINE]

  • Ruppert J, Schütt C, Ostermeier D, Peters JH
    Down-regulation and release of CD14 on human monocytes by IL-4 depends on the presence of serum or GM-CSF.
    Adv Exp Med Biol. 1993;329:281-6.
    PMID: 7691031 [PubMed - indexed for MEDLINE]


1992
  • Grunwald U, Krüger C, Westermann J, Lukowsky A, Ehlers M, Schütt C
    An enzyme-linked immunosorbent assay for the quantification of solubilized CD14 in biological fluids.
    J Immunol Methods. 1992 Nov 5;155(2):225-32.
    PMID: 1385535 [PubMed - indexed for MEDLINE]

  • Schütt C, Schilling T, Krüger C
    Endotoxin neutralization by soluble CD14 in vitro
    Immun Infekt. 1992 Jul;20(3):87-9. German.
    PMID: 1379977 [PubMed - indexed for MEDLINE]

  • Grunwald U, Oeser G, Schröder HD, Ritscher D, Schütt C
    Binding of LPS to CD14
    Immun Infekt. 1992 Jul;20(3):86-7. German.
    PMID: 1379976 [PubMed - indexed for MEDLINE]

  • Schütt C, Schilling T, Grunwald U, Schonfeld W, Krüger C
    Endotoxin-neutralizing capacity of soluble CD14.
    Res Immunol. 1992 Jan;143(1):71-8.
    PMID: 1373513 [PubMed - indexed for MEDLINE]


1991
  • Krüger C, Schütt C, Obertacke U, Joka T, Müller FE, Knoller J, Koller M, Konig W, Schonfeld W
    Serum CD14 levels in polytraumatized and severely burned patients.
    Clin Exp Immunol. 1991 Aug;85(2):297-301.
    PMID: 1713813 [PubMed - indexed for MEDLINE]

  • Schütt C, Schilling T, Krüger C
    sCD14 prevents endotoxin inducible oxidative burst response of human monocytes.
    Allerg Immunol (Leipz). 1991;37(3-4):159-64.
    PMID: 1724353 [PubMed - indexed for MEDLINE]


1990
  • Potzsch M, Schütt C, Nitzsche W
    Results of a study of glucocorticoid receptors in lymphocytes of patients with endogenous depression
    Psychiatr Neurol Med Psychol (Leipz). 1990 Aug;42(8):479-84. German.
    PMID: 2247528 [PubMed - indexed for MEDLINE]

  • Schütt C
    Monocyte markers
    Acta Histochem Suppl. 1990;39:333-7. Review. German.
    PMID: 2080277 [PubMed - indexed for MEDLINE]

  • Jonas L, Schütt C, Neels P, Walzel H, Siegl E
    Electron microscopic study of receptor mediated endocytosis of a monoclonal antibody (RoMo-1) against the surface marker CD 14 of human monocytes.
    Acta Histochem Suppl. 1990;39:339-44.
    PMID: 1706877 [PubMed - indexed for MEDLINE]


1989
  • Jonas L, Schütt C, Neels P, Walzel H, Siegl E
    Electron microscopic visualization of receptor internalization induced by a monoclonal antibody recognizing the monocyte specific glycoprotein CD 14.
    Acta Histochem. 1989;85(2):167-73.
    PMID: 2472729 [PubMed - indexed for MEDLINE]

  • Schütt C, Horejsi V, Walzel H, Siegl E
    Characterization of a monoclonal antibody recognizing a monomorphic determinant of DR antigens.
    Biomed Biochim Acta. 1989;48(4):359-63.
    PMID: 2473743 [PubMed - indexed for MEDLINE]

  • Schütt C, Pfuller U, Siegl E, Walzel H, Franz H
    Selective killing of human monocytes by an immunotoxin containing partially denatured mistletoe lectin I.
    Int J Immunopharmacol. 1989;11(8):977-80.
    PMID: 2613400 [PubMed - indexed for MEDLINE]


1988
  • Schütt C, Ringel B, Nausch M, Bazil V, Horejsi V, Neels P, Walzel H, Jonas L, Siegl E, Friemel H
    Human monocyte activation induced by an anti-CD14 monoclonal antibody.
    Immunol Lett. 1988 Dec;19(4):321-7.
    PMID: 2468604 [PubMed - indexed for MEDLINE]

  • Schütt C, Westphal HJ, Kaben U, Goan SR, Holzheidt G, Nausch M, Schulze HA
    Effects of ketoconazole on the immune system. III. In vitro testing of ketoconazole and therapy follow-up in chronic dermatophytoses
    Mycoses. 1988 Jan;31(1):52-8. German.
    PMID: 3374523 [PubMed - indexed for MEDLINE]

  • Schütt C, Siegl E, Holzheidt G, Claus R, Stosiek P, Kasper M, Walzel H, Schulz U, Friemel H
    A monoclonal antibody against peripheral human blood monocytes (RoMo-1)
    Allerg Immunol (Leipz). 1988;34(1):17-26. German.
    PMID: 3041787 [PubMed - indexed for MEDLINE]


1987
  • Schütt C, Kopp J, Volk HD, Jahn S, Potzsch M
    Effects of ketoconazole on the immune system. II. Studies of the mechanism of action
    Mykosen. 1987 Dec;30(12):559-73. German.
    PMID: 3502419 [PubMed - indexed for MEDLINE]

  • Schütt C, Werner H, Goan SR, Erdmann D, Potzsch M, Claus R, Schulze HA, Kaben U
    Effects of ketoconazole on the immune system. I. In vitro effects on lymphocyte functions
    Mykosen. 1987 Sep;30(9):412-8. German.
    PMID: 3696171 [PubMed - indexed for MEDLINE]

  • Schütt C, Eggers G, Wegener S, Seyfarth M, Peters E, Mach M, Erdmann D
    X-linked hypogammaglobulinaemia with a late secretion defect. A family study.
    Folia Haematol Int Mag Klin Morphol Blutforsch. 1987;114(3):382-9.
    PMID: 2444512 [PubMed - indexed for MEDLINE]